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Related Concept Videos

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Chronic Obstructive Pulmonary Disease01:22

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Chronic Obstructive Pulmonary Disease-I: Introduction01:20

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Other Pulmonary Disorders01:17

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Related Experiment Video

Updated: Aug 31, 2025

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
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Concomitant Interstitial Lung Disease With Psoriasis.

Prabin Kharibam1, Sushma Laishram2, Nikita Choudhary3

  • 1Department of Internal Medicine, All India Institute of Medical Sciences Rishikesh, Rishikesh, IND.

Cureus
|August 22, 2022
PubMed
Summary
This summary is machine-generated.

Psoriasis may be linked to interstitial lung disease, even without immunosuppressant use. This case highlights the potential for immune dysfunction from psoriasis to cause lung fibrosis, emphasizing monitoring lung and skin lesions.

Keywords:
idiopathic pulmonary fibrosis (ipf)interstitial lung diseasenon-specific interstitial lung disease (nsip)psoriasisusual interstitial pneumonia (hip)

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Area of Science:

  • Pulmonology
  • Dermatology
  • Immunology

Background:

  • Interstitial lung disease (ILD) is rarely associated with psoriasis, often as drug-induced pneumonitis from immunosuppressants.
  • Simultaneous occurrence of psoriasis and interstitial pneumonia is infrequently reported, with no clear direct association established.
  • This study investigates a potential direct link between psoriasis and ILD independent of medication.

Observation:

  • A 55-year-old male with psoriasis and hypertension presented with neurological symptoms and exertional dyspnea.
  • Diagnostic workup confirmed interstitial lung disease.
  • The patient had no history of immunosuppressant or biologic use.

Findings:

  • The patient was diagnosed with interstitial lung disease.
  • Absence of immunosuppressant use suggests a non-drug-induced etiology.
  • Psoriasis-related immune dysfunction is hypothesized as a cause of lung fibrotic changes.

Implications:

  • This case suggests a potential direct association between psoriasis and interstitial lung disease.
  • Immune dysregulation in psoriasis may contribute to pulmonary fibrosis.
  • Close monitoring of both skin and lung manifestations is crucial for early diagnosis of psoriasis-associated pneumonia.