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Related Concept Videos

Teeth01:15

Teeth

606
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
606

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Structure, function, and productivity from the National Dental Practice-Based Research Network.

Gregg H Gilbert1, Jeffrey L Fellows2, Veerasathpurush Allareddy3

  • 1Department of Clinical and Community Sciences, School of Dentistry, University of Alabama at Birmingham, Birmingham, AL, USA.

Journal of Clinical and Translational Science
|August 22, 2022
PubMed
Summary
This summary is machine-generated.

The National Dental Practice-Based Research Network (PBRN) has successfully engaged diverse practitioners and patients nationwide, producing significant scientific output. Its structure supports high-impact research beyond traditional academic settings.

Keywords:
Research infrastructuremetricsmulticenter studiespractice patternspractice-based research networks

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Area of Science:

  • Dental research infrastructure and network organization.
  • Clinical research methodology and practice-based research.

Background:

  • The National Dental Practice-Based Research Network (PBRN) was established in 2005 and expanded nationwide in 2012, with further organizational changes in 2019.
  • The network aims to foster collaborative research involving dental practitioners and patients in real-world settings.

Purpose of the Study:

  • To describe the current structure and operational functions of the National Dental PBRN.
  • To quantify the scientific productivity and impact of the network's research activities since its inception in 2005.

Main Methods:

  • The network comprises a national Administrative and Resource Center, regional and specialty nodes across the US, and a Network Coordinating Center.
  • Studies are funded through investigator-initiated grants.
  • Scientific productivity is measured using metrics such as the number of publications and the Relative Citation Ratio (RCR).

Main Results:

  • To date, 58 studies have been completed or are in development, covering diverse topics and study designs.
  • Enrollment included 70,665 patients and 19,827 practitioners, with electronic records for an additional 790,493 patients in data-only studies.
  • Network research has resulted in 193 peer-reviewed publications in 62 journals, with a mean RCR of 1.40, indicating above-average influence.

Conclusions:

  • The PBRN model effectively engages practitioners and patients nationally, demonstrating sustained high scientific productivity.
  • This research infrastructure supports clinical scientists in both oral and non-oral health fields.
  • The network provides valuable recruitment avenues outside of traditional academic health centers.