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Updated: Aug 31, 2025

Surgical Closure of Equine Abdomen, Prevention, and Management of Incisional Complications
Published on: May 10, 2024
How Can Negative Pressure Wound Therapy Pay for Itself?-Reducing Complications Is Important
1Department of Orthopaedic Surgery, University of Texas Health Science Center at San Antonio, San Antonio, TX; and.
Incisional negative pressure wound therapy (iNPWT) may reduce surgical site infections (SSI) and associated costs in high-risk orthopaedic trauma patients. This therapy offers potential cost savings of $1381 to $4436 per patient.
Area of Science:
- Orthopaedic Surgery
- Infectious Disease
- Health Economics
Background:
- Surgical site infections (SSIs) are a significant concern in orthopaedic trauma, leading to increased healthcare costs.
- Incisional negative pressure wound therapy (iNPWT) has shown promise in reducing SSI rates across various surgical specialties.
Purpose of the Study:
- To assess the potential cost savings associated with using iNPWT in high-risk orthopaedic trauma patients with specific fracture types (OTA/AO 41C and 43C).
Main Methods:
- A retrospective cohort study utilizing a lower extremity fracture registry at a level-1 trauma center.
- A health economic model was developed using registry data and literature-derived baseline infection rates to evaluate cost savings.
Main Results:
- In patients with OTA/AO 41C and 43C fractures, the overall SSI rate was 10.1%.
- The SSI rate was reduced to 7.4% in patients who received iNPWT.
- The health economic model estimated potential cost reductions of $1381 to $4436 per patient with iNPWT use.
Conclusions:
- Judicious application of iNPWT may lead to significant healthcare cost reductions in patients undergoing open reduction and internal fixation for OTA/AO 41C and 43C fractures.
- iNPWT presents a viable strategy for mitigating the economic burden of SSIs in complex orthopaedic trauma cases.
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