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Updated: Aug 31, 2025

Techniques for the Evolution of Robust Pentose-fermenting Yeast for Bioconversion of Lignocellulose to Ethanol
Published on: October 24, 2016
Current Ethanol Production Requirements for the Yeast Saccharomyces cerevisiae
Flávia da Silva Fernandes1, Érica Simplício de Souza2, Lívia Melo Carneiro3
1Postgraduate Program in Genetics, Conservation and Evolutionary Biology-GCBEv, National Institute for Amazonian Research (INPA), Manaus, Brazil.
Abstract:
An increase in global energy demand has caused oil prices to reach record levels in recent times. High oil prices together with concerns over CO2 emissions have resulted in renewed interest in renewable energy. Nowadays, ethanol is the principal renewable biofuel. However, the industrial need for increased productivity, wider substrate range utilization, and the production of novel compounds leads to renewed interest in further extending the use of current industrial strains by exploiting the immense, and still unknown, potential of natural yeast strains. This review seeks to answer the following questions: (a) which characteristics should S. cerevisiae have for the current production of first- and second-generation ethanol? (b) Why are alcohol-tolerance and thermo-tolerance characteristics required? (c) Which genes are related to these characteristics? (d) What are the advances that can be achieved with the isolation of new organisms from the environment?
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