Related Experiment Video
Updated: Aug 31, 2025

10:27
In Vivo Morphometric Analysis of Human Cranial Nerves Using Magnetic Resonance Imaging in Menière's Disease Ears and Normal Hearing Ears
Published on: February 21, 2018
10.7K
Predicting positive cochlear endolymphatic hydrops on magnetic resonance images
Kao-Tsung Lin1, Chi-Ju Lu2, Yi-Ho Young1
1Department of Otolaryngology National Taiwan University Hospital Taipei Taiwan.
Laryngoscope Investigative Otolaryngology
|August 24, 2022
Summary
Audiological results can predict cochlear endolymphatic hydrops (EH) in Meniere
Area of Science:
- Otolaryngology
- Radiology
- Audiology
Background:
- Meniere's disease (MD) is characterized by endolymphatic hydrops (EH).
- Magnetic resonance (MR) imaging is used to detect EH, but its correlation with audiological findings requires further investigation.
Purpose of the Study:
- To correlate audiological results with MR imaging findings to predict positive cochlear endolymphatic hydrops (EH) in patients with Meniere's disease (MD).
Main Methods:
- A retrospective study involving 40 definite MD patients.
- Patients were divided into two groups based on MR imaging findings of cochlear EH (positive or negative).
- An inner ear test battery and MR imaging using the HRDROPS-Mi2 technique were performed.
Main Results:
- Mean hearing levels at low frequencies (125-1000 Hz) were significantly worse in patients with positive EH on MR images.
- Specific cutoff hearing thresholds at 125, 250, and 500 Hz were identified to predict positive cochlear EH.
- A sum of low-frequency hearing thresholds >100 dBHL predicted positive cochlear EH in 80% of cases, compared to 30% in the negative EH group.
Conclusions:
- A sum of low-frequency hearing levels >100 dBHL can predict positive cochlear EH on MR images in definite MD patients.
- For MD patients with a sum of low-frequency hearing levels <100 dBHL, MR imaging may be postponed due to potential resolution of EH.
- This correlation aids in the diagnostic approach for Meniere's disease.

