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Updated: Aug 31, 2025

Assessing Urinary Tract Junction Obstruction Defects by Methylene Blue Dye Injection
Published on: October 12, 2017
Recurrent UPJ obstruction following paediatric pyeloplasty is associated with an initial <2.5cm incision open
Fadi Zu'bi1, Fardod O'Kelly2, Walid A Farhat3
1Department of Urology, Rambam Health Care Campus, Haifa, Israel; Department of Urology, The Nazareth Hospital EMMS, Nazareth, Israel.
Insights
Open pyeloplasty increases complication risks in children, including recurrent obstruction and need for revision surgery. Laparoscopic pyeloplasty may offer better outcomes by reducing missed crossing vessel identification during initial repair.
Area of Science:
- Pediatric Urology
- Surgical Outcomes Research
Background:
- Pyeloplasty is a common procedure for pediatric ureteropelvic junction obstruction.
- The choice of surgical approach may influence patient outcomes and complication rates.
Purpose of the Study:
- To identify risk factors impacting surgical outcomes in pediatric pyeloplasty.
- To investigate if the operative approach (open vs. laparoscopic) affects these outcomes.
Main Methods:
- Retrospective cohort study of 185 pediatric pyeloplasty cases (2008-2017).
- Evaluation of clinicodemographic and operative characteristics.
- Analysis of complications, re-stenosis, and revision rates using bivariate and multivariate logistic regression.
Main Results:
- Open pyeloplasty was an independent predictor of overall complications, recurrent UPJ obstruction, and redo-pyeloplasty compared to laparoscopic approach.
- Higher rates of missed crossing vessels were noted in redo-pyeloplasty cases initially treated with open surgery.
- Complications occurred in 11.4% of patients, with 5.4% requiring revision pyeloplasty.
Conclusions:
- Initial open pyeloplasty is associated with increased future complications, potentially due to missed crossing vessels.
- Laparoscopic pyeloplasty may lead to better long-term outcomes.
- Surgeons should consider the risk of missed vascular anomalies in open pyeloplasty procedures.
Objectives:
To determine the risk factors that affect surgical outcomes for pediatric pyeloplasty, and whether this may be related to the choice of operative approach.
Methods:
A retrospective cohort study was performed to evaluate clinicodemographic and operative characteristics of children undergoing dismemberment pyeloplasty by 2 senior pediatric urologists in our tertiary institution between Jan 2008 - Dec 2017. Outcomes included overall complications, re-stenosis, and revision pyeloplasty based on clinic-radiological parameters. Bivariate analysis with Chi-square and Mann-Whitney U test followed by multivariate logistic regression with backward likelihood analysis determined an adjusted effect estimate of the identified significant indicators for inferior peri-operative outcomes related to management.
Results:
A total of 185 (93 open, 92 Laparoscopic) cases with an average follow-up of 31.3±27.4 months were analyzed. Complications occurred in 21 (11.4%) patients. 12 (6.5%) experienced recurrent UPJ obstruction with 10 (5.4%) undergoing redo-pyeloplasty. Of these, 9 were performed open and 1 laparoscopically. Multivariate logistic regression identified open pyeloplasty as an independent predictor for overall complications (HR 3.29, 95%CI 1.14, 9.51), recurrent UPJ obstruction (HR 49.8, 95%CI 3.09, 803.2) and redo-pyeloplasty (HR 9.75, 95%CI 1.21, 78.6) compared to a laparoscopic approach. Missed crossing vessels were identified in seven redo-cases, which all were from prior open pyeloplasty.
Conclusions:
An initial open approach was identified as an independent predictor of future complications due to a higher incidence missed crossing vessels at initial repair. Surgeons need to remain especially mindful of this phenomenon when working in a confined open field.
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