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[Expression of heat-shock proteins in neuroblastoma cells differing genetically in thermal sensitivity]
Abstract:
Electrophoretic analysis of cell proteins of 3 mouse neuroblastoma strains differing in thermostability has shown that a distinctive feature of one of the strains (stable to the action of temperature at 44 degrees C) is the accumulation under normal conditions (37 degrees C) of heat shock protein with the molecular mass of 70 kD. Such accumulation of the specific protein does not take place in cells of the thermosensitive strain, stable to temperature of 40 degrees C.