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The unique effect of TDP-43 on hippocampal subfield morphometry and cognition

Ashley Heywood1, Jane Stocks1, Julie A Schneider2

  • 1Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

Neuroimage. Clinical
|August 25, 2022
PubMed
Abstract

No abstract available in PubMed .

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The hippocampus, a critical brain structure, plays an essential role in memory processing, particularly in the formation and retrieval of memory. This small, seahorse-shaped region is located within the medial temporal lobe, with one hippocampus in each brain hemisphere. Experimental studies involving lesions in the hippocampi of rats have demonstrated significant impairments in tasks such as object recognition and maze navigation, indicating the hippocampus involvement in both recognition and...
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