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Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
Published on: December 19, 2020
Prognostic Value of Chest-Computed Tomography in Patients with COVID-19
Gökhan Perincek1, Canver Önal2, Timor Omar3
1Department of Chest Disease, Kars Harakani State Hospital, Kars 36200, Turkey.
Insights
Chest CT scans can predict COVID-19 patient outcomes. A higher global CT score indicates a greater risk of in-hospital mortality, aiding in prognosis.
Area of Science:
- Radiology
- Infectious Diseases
- Critical Care Medicine
Background:
- Chest CT imaging is crucial for diagnosing COVID-19.
- Prognostic data from chest CT in COVID-19 patients remains limited.
Purpose of the Study:
- To investigate the prognostic value of chest CT scans in hospitalized COVID-19 patients.
- To determine if chest CT findings can predict in-hospital mortality.
Main Methods:
- Retrospective analysis of 521 symptomatic COVID-19 patients.
- Application of a semi-quantitative CT severity scoring system.
- Comparison of clinical, laboratory, and CT characteristics between survivors and non-survivors.
Main Results:
- The global CT score was significantly higher in non-survivors (p < 0.001).
- A global CT score cutoff of 5.5 predicted in-hospital mortality with 74% sensitivity and 73% specificity.
- Global CT score, age, C-reactive protein, and diabetes were independent predictors of mortality.
Conclusions:
- The global CT score offers valuable prognostic information for symptomatic COVID-19 patients.
- Chest CT severity scoring can aid in assessing mortality risk.
Abstract:
Background: The diagnostic value for chest CT has been widely established in patients with COVID-19. However, there is a lack of satisfactory data about the prognostic value of chest CTs. This study investigated the prognostic value of chest CTs in COVID-19 patients. Materials and Methods: A total of 521 symptomatic patients hospitalized with COVID-19 were included retrospectively. Clinical, laboratory, and chest CT characteristics were compared between survivors and non-survivors. Concerning chest CT, for each subject, a semi-quantitative CT severity scoring system was applied. Results: Most patients showed typical CT features based on the likelihood of COVID-19. The global CT score was significantly higher in non-survivors (median (IQR), 1 (0−6) vs. 10 (5−13), p < 0.001). A cut-off value of 5.5 for the global CT score predicted in-hospital mortality with 74% sensitivity and 73% specificity. Global CT score, age, C-reactive protein, and diabetes were independent predictors of in-hospital mortality. The global CT score was significantly correlated with the C-reactive protein, D-dimer, pro-brain natriuretic peptide, and procalcitonin levels. Conclusion: The global CT score could provide valuable prognostic data in symptomatic patients with COVID-19.
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