Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Selective electrochemical methanol to formate conversion via direct CHO hydroxylation on Pt<sup>δ+</sup>-Pt<sup>δ-</sup> dipoles.

Nature communications·2026
Same author

Intelligent water environment diagnosis and treatment center: A machine learning framework for automated surface water pollution management.

Water research·2026
Same author

Effects of replacing dietary glucose with fructose on intestinal morphology, oxidative status, and epithelial responses in weaned pigs.

Journal of animal science·2026
Same author

The impact of elective physical education on high school students' core PE competencies: a quasi-experimental study.

Frontiers in psychology·2026
Same author

Synergistic role of microbial osmoregulation and electron transfer on enhancing high-salinity battery discharge wastewater treatment under electrochemical stimulation.

Water research·2026
Same author

A spatiotemporal resolution to genetic redundancy: MIR164 diversification coordinates development and metabolism in Brassica.

The Plant journal : for cell and molecular biology·2026
Same journal

Investigating Nonlinear Fatigue Damage Evolution of SBS-Modified Asphalt Mixtures with Physical Gel Structure.

Gels (Basel, Switzerland)·2026
Same journal

Nano-Iron (III) Oxide-Doped Poly (Itaconic Acid-Co-Acrylamide)/Sodium Alginate Hydrogel for Saline-Alkali Soil Amelioration and Wheat Growth.

Gels (Basel, Switzerland)·2026
Same journal

Evaluation of Starch-Derived Hydrogel Systems for Artifact-Cleaning Applications.

Gels (Basel, Switzerland)·2026
Same journal

Bioorthogonally Cross-Linked Injectable PEG Hydrogel with Robust Hemostatic and Antibacterial Properties.

Gels (Basel, Switzerland)·2026
Same journal

Robust Polyurethane Hydrogels Based on Dynamic Disulfide Bonds and Pendant Tertiary Amines with Room-Temperature Self-Healing and pH Responsiveness.

Gels (Basel, Switzerland)·2026
Same journal

An Environmentally Tolerant 5A Hydrogel with Photothermal Effect for Frostbite Treatment.

Gels (Basel, Switzerland)·2026
See all related articles

Related Experiment Video

Updated: Aug 31, 2025

Synthesis of Strong Adhesive Hydrogel, Gelatin O-Nitrosobenzaldehyde
07:04

Synthesis of Strong Adhesive Hydrogel, Gelatin O-Nitrosobenzaldehyde

Published on: November 11, 2022

2.6K

Antibacterial and Angiogenic Poly(ionic liquid) Hydrogels.

Chengju Sheng1, Xuemei Tan1, Qing Huang1

  • 1School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China.

Gels (Basel, Switzerland)
|August 25, 2022
PubMed
Summary
This summary is machine-generated.

New antibacterial hydrogels accelerate wound healing by killing bacteria and promoting blood vessel repair. These advanced wound dressings offer a promising strategy for faster and more effective tissue regeneration.

Keywords:
anti-inflammatoryantibacterial hydrogelsdeferoxamineimidazolium poly(ionic liquids)vascular repair

More Related Videos

An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart
10:28

An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart

Published on: June 7, 2015

17.4K
Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications
09:39

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications

Published on: February 7, 2021

8.1K

Related Experiment Videos

Last Updated: Aug 31, 2025

Synthesis of Strong Adhesive Hydrogel, Gelatin O-Nitrosobenzaldehyde
07:04

Synthesis of Strong Adhesive Hydrogel, Gelatin O-Nitrosobenzaldehyde

Published on: November 11, 2022

2.6K
An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart
10:28

An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart

Published on: June 7, 2015

17.4K
Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications
09:39

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications

Published on: February 7, 2021

8.1K

Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Wound Healing Research

Background:

  • Wound repair is significantly impaired under low-hydration conditions, necessitating advanced wound dressings.
  • Hydrogels offer a moist, gas-permeable environment crucial for effective wound healing.
  • Antibacterial hydrogels provide sustained antimicrobial activity and minimize cellular damage.

Purpose of the Study:

  • To develop novel antibacterial hydrogels for accelerated wound healing.
  • To investigate the antibacterial efficacy and anti-inflammatory properties of the synthesized hydrogels.
  • To evaluate the hydrogels' potential in promoting endothelial cell migration and angiogenesis.

Main Methods:

  • Synthesis of two antibacterial agents: imidazolium poly(ionic liquids) with sulfhydryl (Imidazole-SH) and ε-Poly(lysine) with sulfhydryl (EPL-SH).
  • Preparation of hydrogels via "thiol-ene" click reaction using lysine as a cross-linker and incorporating Deferoxamine (DFO).
  • In vitro assessment of antibacterial activity against *Escherichia coli* and *Staphylococcus aureus*, anti-inflammatory effects against Lipopolysaccharide (LPS), and promotion of human umbilical vein endothelial cell (HUVEC) migration and angiogenesis.

Main Results:

  • The synthesized hydrogels demonstrated effective killing of *E. coli* and *S. aureus*.
  • The hydrogels successfully reduced inflammatory responses induced by LPS.
  • DFO-incorporated hydrogels significantly promoted HUVEC migration and enhanced vascular repair in angiogenesis assays.

Conclusions:

  • The developed DFO-incorporated antibacterial hydrogels show significant potential as advanced wound dressings.
  • These hydrogels offer a dual action of combating infection and promoting tissue regeneration.
  • The findings present a novel strategy for improving wound healing outcomes.