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Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
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Value-Based Care in Systemic Therapy: The Way Forward.

Aju Mathew1, Steve Joseph Benny2, Jeffrey Mathew Boby3

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Summary
This summary is machine-generated.

Rising cancer care costs necessitate considering financial toxicity. Implementing value-based care in oncology, focusing on patient value, can mitigate this toxicity and improve healthcare delivery.

Keywords:
cancercost of carefinancial toxicitysystemic therapyvaluevalue-based

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Area of Science:

  • Oncology
  • Health Economics
  • Healthcare Policy

Background:

  • The escalating cost of cancer care presents a significant challenge in healthcare delivery.
  • Financial toxicity, a consequence of cancer therapy expenses, requires attention in clinical practice and policy.
  • Value-based care offers a potential strategy to mitigate the financial burden on patients undergoing cancer treatment.

Purpose of the Study:

  • To explore the concept of value-based care in systemic therapy within oncology.
  • To discuss strategies for incorporating value into cancer care decision-making and policy.
  • To examine methods for measuring and implementing value in routine clinical practice.

Main Methods:

  • Discussion of value-based care principles applied to oncology.
  • Review of strategies including composite value assessment tools for drugs.
  • Consideration of alternative dosing strategies and Health Technology Assessment (HTA) in regulatory processes.

Main Results:

  • Value-based care can enhance the quality of cancer treatment delivery.
  • Composite tools, alternative dosing, and HTA are key strategies for assessing and implementing value.
  • A greater emphasis on the value of therapy is proposed for determining its utilization and cost.

Conclusions:

  • Value-based care is crucial for addressing financial toxicity in cancer treatment.
  • Integrating value assessment into drug evaluation and clinical practice is essential.
  • Prioritizing therapy value can lead to more sustainable and patient-centered oncology care.