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The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
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Sedatives and hypnotics encompass a wide range of substances, each with its unique mechanism of action, uses, and potential adverse effects.
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
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In general, the term ‘aromatic’ indicates a pleasant smell or fragrance from fresh flowers, freshly prepared coffee, etc. In the early history of organic chemistry, many benzene derivatives were isolated from the pleasant odor oils of the plants. For example, vanillin was isolated from the oil of vanilla, methyl salicylate from the oil of wintergreen, and cinnamaldehyde from the oil of cinnamon. They all had a pleasant odor; hence the name aromatic was given.
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Sleep, an essential biological state, involves significant reductions in physical activity, sensory awareness, and interaction with the environment. This complex physiological process is primarily regulated by specific brain regions, notably the hypothalamus and pons, which govern the sleep-wake cycle or circadian rhythm.
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Essential Oils and Melatonin as Functional Ingredients in Dogs.

Domingo Ruiz-Cano1, Ginés Sánchez-Carrasco1, Amina El-Mihyaoui2

  • 1Alinatur Pet Food, S.L., Pol. Ind. Saprelorca, Lorca, 30817 Murcia, Spain.

Animals : an Open Access Journal From MDPI
|August 26, 2022
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Summary

This review explores phytogenics like essential oils (EOs) and melatonin as functional ingredients for dogs. Their combined use in food and topically shows promise for managing stress, anxiety, and hair issues in pets.

Keywords:
dogsessential oilsfunctional ingredientsimproved healthmelatoninnutraceuticalspet foodphytogenics

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Area of Science:

  • Veterinary Nutraceuticals
  • Animal Health and Nutrition
  • Phytogenic Compounds

Background:

  • Nutraceuticals and functional ingredients are increasingly used in animal feed for health benefits.
  • Phytogenics, natural compounds from plants, offer diverse chemical properties and applications.
  • Essential oils (EOs) and melatonin are key phytogenic compounds with therapeutic potential in pets.

Purpose of the Study:

  • To review relevant phytogenics, focusing on essential oils and melatonin for dogs.
  • To discuss their characteristics, applications in food and topical products, and regulatory aspects.
  • To explore the combined use of EOs and melatonin for pet health and well-being.

Main Methods:

  • Comprehensive literature review of scientific studies on phytogenics in canine nutrition.
  • Analysis of chemical properties, physiological effects, and therapeutic applications of EOs and melatonin.
  • Examination of regulatory frameworks for functional ingredients in pet food and topical products.

Main Results:

  • Phytogenics, including polyphenols, isoprenoids, and alkaloids, offer significant health benefits for dogs.
  • Essential oils and melatonin show efficacy in managing stress, anxiety, sleep disorders, and alopecia.
  • Combined application of EOs and melatonin in food supplements and topicals presents innovative therapeutic strategies.

Conclusions:

  • Essential oils and melatonin are valuable nutraceuticals for canine health, with broad application potential.
  • The synergistic use of EOs and melatonin offers promising solutions for common pet dysfunctions.
  • Further research into combined phytogenic and melatonin therapies can advance veterinary care for pets.