Pharmaceutical Coating and Its Different Approaches, a Review.

Area of Science:

• Pharmaceutical Technology
• Materials Science

Background:

• Tablet coating is a common yet critical process for oral solid dosage forms.
• It enhances drug delivery, meets clinical needs, and adds value to pharmaceutical products.

Purpose of the Study:

• To review film coating processes and polymers used in solid dosage forms.
• To highlight the importance of coating uniformity and technological advancements.

Main Methods:

• Review of existing literature on tablet coating techniques (solvent-based and solvent-free).
• Discussion of computational modeling and experimental evaluation for process optimization.
• Focus on polymers, coating equipment, and evaluation methods.

Main Results:

• Different coating techniques offer advantages and disadvantages, requiring continuous modification.
• Inter- and intra-batch uniformity of coating is crucial for product quality, especially for medicated coatings.
• Computational modeling and experimental evaluation aid in optimizing operational parameters, saving time and cost.

Conclusions:

• Film coating significantly impacts the characteristics and efficacy of oral solid dosage forms.
• Advancements in coating technology, materials, and evaluation are essential for pharmaceutical innovation.
• Optimized coating processes ensure product quality and therapeutic effectiveness.