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Poor long-term recovery after critical COVID-19 during 12 months longitudinal follow-up

Ing-Marie Larsson1, Michael Hultström2, Miklos Lipcsey3

  • 1Anesthesia and Intensive Care Medicine, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.

Intensive & Critical Care Nursing
|August 26, 2022
PubMed

Insights

Former intensive care patients with COVID-19 experienced significant cognitive, physical, and psychological burdens. While cognitive function improved over time, return to work remained challenging for those with a higher burden of illness.

Area of Science:

  • Intensive Care Medicine
  • Infectious Diseases
  • Rehabilitation Medicine

Background:

  • COVID-19 survivors treated in intensive care units (ICUs) face prolonged health challenges.
  • Understanding the long-term burden of illness and impact on daily life is crucial for patient recovery.
  • The first wave of COVID-19 provided an early opportunity to study these post-ICU effects.

Purpose of the Study:

  • To describe the burden of illness in patients treated for COVID-19 in intensive care.
  • To assess the impact on health status, cognitive, physical, and psychological outcomes.
  • To evaluate the effect on the working situation of these survivors.

Main Methods:

  • A prospective cohort study design was employed.
  • Data were collected from patients at a single university hospital ICU in Sweden.
  • Validated instruments assessed outcomes at four and 12 months post-ICU discharge.

Main Results:

  • 82% of participants reported persistent general fatigue at both follow-ups.
  • A significant proportion reported lower health status than the general population.
  • Cognitive impairment decreased from 52% at 4 months to 31% at 12 months (p=0.029).
  • Sick leave decreased, but full-time employment rates remained stable.

Conclusions:

  • Patients treated for COVID-19 in intensive care experience significant cognitive, physical, and psychological sequelae.
  • Cognitive function showed improvement by 12 months post-discharge.
  • A higher burden of illness was associated with difficulties in returning to work.
Abstract

Keywords:
COVID-19Follow-upIntensive careLong-term outcome

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