Comparing a knowledge-based 3D reconstruction algorithm to TomTec 3D echocardiogram algorithm in measuring left...

Area of Science:

• Cardiology
• Medical Imaging
• Pediatric Health

Background:

• Three-dimensional echocardiography (3DE) is advancing cardiac volume measurement.
• Vendor-neutral analysis software for 3DE is limited.
• Ventripoint Medical System Plus (VMS3.0+) uses an MRI database for ventricular and atrial morphology.

Purpose of the Study:

• To compare left ventricular (LV) and left atrial (LA) volumes measured by VMS3.0+ against Tomtec echocardiography analysis software.
• To evaluate the accuracy and efficiency of VMS3.0+ for pediatric cardiac imaging.

Main Methods:

• Prospective recruitment of 98 healthy pediatric controls (0-18 years).
• Acquisition of 3D DICOM datasets for LV and LA.
• Measurement of LV and LA volumes and ejection fractions using both VMS3.0+ and Tomtec Image Arena.
• Statistical analysis included Pearson correlation, Bland-Altman plots, and intraclass coefficients (ICC).

Main Results:

• Very good correlation found between VMS3.0+ and Tomtec for LV systolic (r²=0.88, ICC=0.89) and diastolic (r²=0.88, ICC=0.90) volumes.
• Strong correlation also observed for LA diastolic (r²=0.75, ICC=0.89) and systolic (r²=0.88, ICC=0.91) volumes.
• VMS3.0+ analysis time was significantly shorter than Tomtec for both LV and LA measurements (p < 0.001).

Conclusions:

• Knowledge-based (VMS3.0+) and 3D (Tomtec) algorithms demonstrate high agreement for 3DE-derived LA and LV volumes in pediatric patients.
• VMS3.0+ provides a faster alternative for volumetric analysis compared to Tomtec.
• These findings support the use of VMS3.0+ for accurate and efficient pediatric cardiac volume assessment.