[Volatile fractions of essential oil-based phytoncides as a component of therapeutic-rehabilitative complexes in...

Three samples of essential oil (EO) were studied. Experiments on the cultures of human fetal lung fibroblasts showed 2 samples of EO in concentrations of 0.25-2.5 micrograms/ml to considerably stimulate DNA synthesis. Spray administration of one of the samples to guinea-pigs in line with egg powder sensitization for two more days resulted in a complete discontinuation of the respiratory allergic reaction to inhalation of a resolving dose of the antigen 12 days after sensitization. The evaluation of 96 patients with chronic bronchitis (mainly obstructive) subjected to daily 40-minute stay in the atmosphere containing natural concentrations (about 0.1 mg/m3) of EO volatile fractions, showed a significant increase in the permeability of the respiratory tracts (Tiffeneau's index) and a decrease in IgE total serum level.