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Maxillary and mandibular odontogenic myxomas: case report
Jinane Kharbouch1, Zakaria Aziz1, Zahira Benzenzoum1
1Maxillo Facial Surgery Department, University Hospital Center Mohammed VI, Marrakech, Morocco.
The Pan African Medical Journal
|August 29, 2022
Summary
Odontogenic myxomas are rare, locally aggressive tumors of the jaw. Early diagnosis and appropriate treatment, ranging from conservative to radical surgery, are crucial to prevent recurrence.
Area of Science:
- Oral and Maxillofacial Surgery
- Oncology
- Pathology
Background:
- Odontogenic myxomas are rare, benign tumors with a high potential for local infiltration and destruction.
- Their clinical and radiological features are often non-specific, mimicking other benign and malignant jaw lesions.
Observation:
- This study presents two cases of odontogenic myxoma in the maxilla and mandible, presenting as slowly enlarging facial swellings.
- Computed tomography revealed large, unilocular, homogeneous lesions causing cortical thinning, rupture, and displacement of surrounding tissues.
- Histological examination was essential for definitive diagnosis due to ambiguous clinical and radiological findings.
Findings:
- Both cases demonstrated a locally aggressive pattern despite the benign nature of the tumor.
- Large tumors necessitated extensive surgical resection, including maxillectomy and mandibulectomy.
- Histological confirmation is the gold standard for diagnosing odontogenic myxoma.
Implications:
- Clinicians must consider odontogenic myxoma in the differential diagnosis of jaw swellings.
- Treatment strategies should be tailored to tumor size and aggressiveness, with conservative management for small lesions and radical excision for larger ones to minimize recurrence risk.

