Electrospun nanofiber-based glucose sensors for glucose detection

Area of Science:

• Biomedical Engineering
• Materials Science
• Analytical Chemistry

Background:

• Diabetes is a growing global health concern characterized by chronic metabolic dysregulation and severe complications.
• Continuous glucose monitoring is vital for effective diabetes management, prevention, and diagnosis.
• Electrospun nanofibers represent a promising class of advanced nanomaterials for biosensing applications.

Purpose of the Study:

• To review glucose sensors utilizing electrospun nanofibers.
• To discuss the principles, methods, and applications of these advanced glucose sensors.
• To evaluate the advantages, disadvantages, and future commercialization potential of electrospun nanofiber-based glucose sensors.

Main Methods:

• Review of electrospinning principles and their application in glucose sensor fabrication.
• Analysis of polymer and nanomaterial utilization in electrospun nanofiber glucose sensors.
• Comparison of enzymatic and non-enzymatic detection mechanisms in nanofiber-based sensors.

Main Results:

• Electrospun nanofibers demonstrate significant potential for high-level biosensing, offering efficient and stable glucose detection.
• Both polymers and nanomaterials integrated into nanofibers enhance glucose sensor performance.
• Enzymatic and non-enzymatic approaches using nanofibers show distinct advantages and applications.

Conclusions:

• Electrospun nanofiber-based glucose sensors offer a promising platform for reliable, continuous blood glucose monitoring.
• Further research and development are needed to address current limitations and optimize commercial viability.
• These advanced sensors hold potential for improved diabetes care and management strategies.