Improved treatment robustness of postoperative breast cancer radiotherapy including supraclavicular nodes

A combination of a three-dimensional conformal radiation therapy (3D-CRT) plan with a dose gradient of the chest wall area and a volumetric modulated arc therapy (VMAT) plan of the supraclavicular area might improve the dose distribution robustness in the junction. To investigate the impact of patient motion on the dose distribution, hybrid 3D-CRT and VMAT plans were recalculated by shifting the isocenter of the VMAT plan. Compared to the nominal plan, the target D_98% for high- vs low-dose gradients decreased by 24% vs 12%. Hybrid VMAT with a low-dose gradient 3D-CRT plan was found to be robust towards patient motion.