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Structural Brain Correlates of Childhood Inhibited Temperament: An ENIGMA-Anxiety Mega-analysis.
Janna Marie Bas-Hoogendam1, Rachel Bernstein2, Brenda E Benson2
1Leiden University, Leiden, the Netherlands; Leiden University Medical Center, Leiden, the Netherlands; Leiden Institute for Brain and Cognition, Leiden, the Netherlands; National Institute of Mental Health, Bethesda, Maryland.
Behavioral inhibition, a temperament trait involving avoidance of the unfamiliar, is moderately heritable. It can be measured from infancy through childhood using behavioral observations and caregiver reports.
Area of Science:
- Psychology
- Developmental Psychology
- Behavioral Science
Background:
- Temperament comprises stable individual differences in behavioral and emotional tendencies.
- Behavioral inhibition (BI) is a key temperament trait characterized by withdrawal from unfamiliar stimuli.
- BI is observable from infancy and persists across contexts and lifespan.
Purpose of the Study:
- To define and characterize behavioral inhibition (BI) as a fundamental temperament trait.
- To highlight the heritability and cross-species relevance of BI.
- To outline methods for quantifying BI levels in humans.
Main Methods:
- Behavioral observations in infancy and early childhood.
- Caregiver and teacher reports.
- Self-report questionnaires for retrospective and current BI levels.
Main Results:
- Behavioral inhibition is a well-defined and measurable temperament trait.
- BI demonstrates moderate heritability.
- Quantification methods are available from infancy through adulthood.
Conclusions:
- Behavioral inhibition is a stable, heritable temperament trait with significant implications for understanding individual differences.
- Early identification and measurement of BI are possible through various methods.
- Understanding BI contributes to developmental psychology and behavioral science research.
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