Updated Results of the COVID-19 in MS Global Data Sharing Initiative: Anti-CD20 and Other Risk Factors Associated

Steve Simpson-Yap1, Ashkan Pirmani2, Tomas Kalincik2

  • 1From the CORe (S.S.-Y., T.K., S.S.), Department of Medicine, and Neuroepidemiology Unit (S.S.-Y., N.N.), Melbourne School of Population & Global Health, The University of Melbourne; Menzies Institute for Medical Research (S.S.-Y.), University of Tasmania, Australia; ESAT-STADIUS (A.P., E.D.B., L.G., T.P., Y.M.), KU Leuven; Biomedical Research Institute-Data Science Institute (A.P., L.G., T.P.), Hasselt University, Belgium; MS Centre (T.K., L.M.P.), Department of Neurology, Royal Melbourne Hospital, Australia; Department of Medical Informatics (T.K.), University Medical Center Göttingen, Germany; MS International Federation (A.H., N.R.), London, United Kingdom; Department of Clinical Neuroscience (J.A.H., T.S.), Swedish MS Registry, Karolinska Institutet, Sweden; Department of Neurology (G.E.), CHU Pontchaillou, France; iConquerMS People-Powered Research Network (R.M., H.S.), Accelerated Cure Project for MS, Waltham, MA; NeuroTransData Study Group (A.B.B., S.B.), NeuroTransData, Neuburg an der Donau, Germany; German MS-Register by the National MS Society (A. Stahmann), MS Forschungs- und Projektentwicklungs-gGmbH; UK MS Register (R.M.M., R.S.N.), Swansea University; COViMS (A. Salter, B.B.); Division of Biostatistics (A. Salter), Washington University in St. Louis; Department of Neuroscience (A.V.d.W., H.B.), Central Clinical School, Monash University, Australia; Dokuz Eylul University (S.O.), İzmir; Department of Neurology (C.B.), Karadeniz Technical University, Trabzon; Department of Neurology (R.K.), University of Hacettepe, Turkey; Amiri Hospital (R.A.), Kuwait; Neurology Department (J.I.R.), Hospital Universitario de CEMIC; RELACOEM (J.I.R., R.N.A.), Buenos Aires, Argentina; The Australian MS Longitudinal Study (I.A.v.d.M.), Menzies Institute for Medical Research, University of Tasmania; ABEM-Brazilian MS Patients Association (G.S.d.O.); The Danish Multiple Sclerosis Registry (M.M.), Departement of Neurology, University Hospital Rigshospitalet, Denmark; Multiple Sclerosis University Center (R.N.A.), Ramos Mejia Hospital-EMA, Argentina; Imperial College London (R.S.N., A.M.), United Kingdom; MS and Demyelinating Diseases, Hospital Británico de Buenos Aires (A.S.C.), EMA, Argentina; Servei de Neurologia-Neuroimmunologia (A.Z.d.T., G.A.), Centre d'Esclerosi Múltiple de Catalunya (Cemcat), Vall d'Hebron Institut de Recerca, Vall d'Hebron Hospital Universitari, Universitat Autònoma de Barcelona, Spain; icometrix (A.D., L.C.), Leuven, Belgium; Queen Mary University London (R.D.), United Kingdom; QMENTA (P.R., V.P.), Barcelona, Spain; and Casa di Cura del Policlinico and Università Vita Salute San Raffaele (G.C.), Italy. liesbet.peeters@uhasselt.be.

Abstract

Related Concept Videos

Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
12.2K
Relative Risk01:12

Relative Risk

Relative risk (RR) is a statistical measure commonly used in epidemiology to compare the likelihood of a particular event occurring between two groups. This metric is important for evaluating the relationship between exposure to a specific risk factor and the probability of a particular outcome. It plays a crucial role in medical research, public health studies, and risk assessment. Relative risk quantifies how much more (or less) likely an event is to occur in an exposed group compared to an...
307
Factors Affecting Drug Response: Overview01:21

Factors Affecting Drug Response: Overview

When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily because their organ functions still need to fully develop, meaning their bodies are not as efficient at metabolizing or eliminating drugs. Additionally, their blood-brain barrier is more permeable than in adults. As a result, high concentrations of drugs can easily penetrate the central nervous system (CNS), potentially leading to neurological...
2.1K
Factors Affecting Illness01:18

Factors Affecting Illness

When a person's physical, emotional, intellectual, social development or spiritual functioning is compromised, this deviation from a healthy normal state is called illness. Illness creates stress that in turn harms individuals. Irritation, anger, denial, hopelessness, and fear are behavioral and emotional changes an individual experiences in the phases of illness. A variety of factors influence a person's health and well-being.
For instance, risk factors are connected to illness,...
4.4K
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
303
Immunodeficiency Diseases01:25

Immunodeficiency Diseases

Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
1.2K