Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Somatosensory, Motor, and Association Cortex01:24

Somatosensory, Motor, and Association Cortex

869
The somatosensory cortex in the parietal lobes is crucial for interpreting sensory data such as touch, temperature, and proprioception. The somatosensory cortex, situated in the parietal lobes, plays a vital role in interpreting sensory information like touch, temperature, and proprioception—awareness of body position. This specialized brain region features an organized structure wherein neurons at the top primarily process sensations originating from the lower body. In contrast, those at...
869
Somatosensation01:33

Somatosensation

38.2K
The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.
38.2K
Sensory Perception: Organization of the Somatosensory System01:11

Sensory Perception: Organization of the Somatosensory System

4.7K
The somatosensory system is the central and peripheral nervous system component that senses and processes touch, pressure, pain, temperature, and body position or proprioception. The process of sensation takes place at three levels:
The receptor level:
The receptor level is the first stage of sensation. It involves the detection of a stimulus by specialized sensory receptors. The stimulus must arrive within the receptor's receptive field. Next, the receptor converts the energy of the...
4.7K
Motor and Sensory Areas of the Cortex01:14

Motor and Sensory Areas of the Cortex

4.5K
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
4.5K
Tactile and Chemical Senses01:27

Tactile and Chemical Senses

342
Tactile senses encompass touch, temperature, and pain, each mediated by specific receptors. Touch receptors detect mechanical energy or pressure against the skin. Sensory fibers from these receptors enter the spinal cord and relay information to the brain stem. Here, most fibers cross over to the opposite side of the brain. The touch information then moves to the thalamus, which projects a map of the body's surface onto the somatosensory areas of the parietal lobes in the cerebral cortex.
342
Thermosensation01:43

Thermosensation

31.7K
Peripheral thermosensation is the perception of external temperature. A change in temperature (on the surface of the skin and other tissues) is detected by a family of temperature-sensitive ion channels called Transient Receptor Potential, or TRP, receptors. These receptors are located on free nerve endings. Those detecting cold temperatures are closer to the surface of the skin than the nerve endings detecting warmth. These thermoTRP channels, while temperature selective, have relatively...
31.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Insular cortex predictions regulate glucose homeostasis.

bioRxiv : the preprint server for biology·2026
Same author

Dynamic rRNA methylation regulates translation in the hematopoietic system and is essential for stem cell fitness.

Blood·2025
Same author

Thalamic opioids from POMC satiety neurons switch on sugar appetite.

Science (New York, N.Y.)·2025
Same author

FENS-Kavli Network of Excellence: Bridging levels and model systems in neuroscience: Challenges and solutions.

The European journal of neuroscience·2023
Same author

History-Dependent Odor Processing in the Mouse Olfactory Bulb.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2017
Same journal

Evolution of Adaptive Non-Shivering Thermogenesis in Mammals.

Physiology (Bethesda, Md.)·2026
Same journal

The Iron Lung: Ferroptosis and Iron Regulation in Aging and Lung Diseases.

Physiology (Bethesda, Md.)·2026
Same journal

RNA-Protein complexes and their role in cell fate.

Physiology (Bethesda, Md.)·2026
Same journal

Ion Channels as Gatekeepers of Fertility: From Uterine Kir7.1 to Sperm CatSper.

Physiology (Bethesda, Md.)·2026
Same journal

Is insulin resistance an adaptive response? Clues from nature.

Physiology (Bethesda, Md.)·2026
Same journal

Physiology in Perspective.

Physiology (Bethesda, Md.)·2026
See all related articles

Related Experiment Video

Updated: Aug 30, 2025

Multi-layer Cortical Ca2+ Imaging in Freely Moving Mice with Prism Probes and Miniaturized Fluorescence Microscopy
10:35

Multi-layer Cortical Ca2+ Imaging in Freely Moving Mice with Prism Probes and Miniaturized Fluorescence Microscopy

Published on: June 13, 2017

31.3K

Physiological Needs: Sensations and Predictions in the Insular Cortex.

Yael Prilutski1, Yoav Livneh1

  • 1Department of Brain Sciences, Weizmann Institute of Science, Rehovot, Israel.

Physiology (Bethesda, Md.)
|August 30, 2022
PubMed
Summary
This summary is machine-generated.

The insular cortex is key to regulating physiological needs like hunger and thirst. This review explores how it works and offers a framework for future research in health and disease.

Keywords:
homeostasisinsular cortexinteroceptionmotivationpredictive coding

More Related Videos

Real-time Analysis of Gut-brain Neural Communication: Cortex wide Calcium Dynamics in Response to Intestinal Glucose Stimulation
07:29

Real-time Analysis of Gut-brain Neural Communication: Cortex wide Calcium Dynamics in Response to Intestinal Glucose Stimulation

Published on: December 29, 2023

734
Quantitative Assessment of Cortical Auditory-tactile Processing in Children with Disabilities
09:38

Quantitative Assessment of Cortical Auditory-tactile Processing in Children with Disabilities

Published on: January 29, 2014

10.9K

Related Experiment Videos

Last Updated: Aug 30, 2025

Multi-layer Cortical Ca2+ Imaging in Freely Moving Mice with Prism Probes and Miniaturized Fluorescence Microscopy
10:35

Multi-layer Cortical Ca2+ Imaging in Freely Moving Mice with Prism Probes and Miniaturized Fluorescence Microscopy

Published on: June 13, 2017

31.3K
Real-time Analysis of Gut-brain Neural Communication: Cortex wide Calcium Dynamics in Response to Intestinal Glucose Stimulation
07:29

Real-time Analysis of Gut-brain Neural Communication: Cortex wide Calcium Dynamics in Response to Intestinal Glucose Stimulation

Published on: December 29, 2023

734
Quantitative Assessment of Cortical Auditory-tactile Processing in Children with Disabilities
09:38

Quantitative Assessment of Cortical Auditory-tactile Processing in Children with Disabilities

Published on: January 29, 2014

10.9K

Area of Science:

  • Neuroscience
  • Physiology
  • Behavioral Science

Background:

  • Physiological needs, such as thirst and hunger, drive motivated behaviors.
  • The insular cortex is increasingly recognized for its role in regulating these needs.
  • Understanding its function is crucial for addressing related health conditions.

Purpose of the Study:

  • To review mechanistic models of insular cortex function in physiological need regulation.
  • To present a framework for testing these models.
  • To guide future research in both healthy and pathological states.

Main Methods:

  • Literature review of existing studies on the insular cortex and physiological needs.
  • Synthesis of prominent mechanistic models.
  • Development of a conceptual and analytical framework.

Main Results:

  • Identified key models explaining insular cortex roles in homeostasis and motivation.
  • Proposed a framework integrating neurobiological and behavioral approaches.
  • Highlighted the need for empirical testing of these models.

Conclusions:

  • The insular cortex plays a central role in the neural circuitry of physiological needs.
  • The proposed framework facilitates rigorous investigation of its functions.
  • This research can inform interventions for disorders related to motivated behavior.