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Updated: Aug 30, 2025

Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma
Published on: April 11, 2018
[Current Therapy Standards for Soft Tissue Sarcomas in the Head and Neck Area - Part 1]
Andreas Dietz1, Bernd Lethaus, Markus Pirlich
1Klinik und Poliklinik für Hals-, Nasen-, Ohrenheilkunde, Universität Leipzig, Leipzig.
Abstract:
The present work discusses soft tissue sarcoma in the head and neck area, due to the new published German S3-Guideline "adult soft tissue sarcoma". The head and neck surgeon plays the central role in the diagnosis and treatment of the vast majority of cases. It is crucial to admit the patients immediately to specialized centers for diagnoses and specific treatment. Regarding correct diagnostic procedures, in contrast to squamous cell carcinoma, a larger accidental excisional biopsy within the tumor tissue is strongly prognostic negative. After confirmation of histology and tumor extension, it is mandatory to discuss the interdisciplinary treatment concept. If possible, introduction of the patient in ongoing clinical studies is key.
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