Progress in the application of sustained-release drug microspheres in tissue engineering

Area of Science:

• Biomaterials Science
• Drug Delivery Systems
• Tissue Engineering

Background:

• Sustained-release drug microspheres are advanced drug delivery systems offering prolonged therapeutic effects.
• Their versatility in formulation and ease of preparation have led to widespread adoption in various biomedical fields.

Purpose of the Study:

• To systematically review the applications of sustained-release drug microspheres in tissue engineering.
• To provide a comprehensive understanding of microsphere types, preparation methods, and their role in regenerative medicine.

Main Methods:

• Literature review of sustained-release drug microspheres in tissue engineering.
• Categorization of microsphere types and their characteristics.
• Summary of preparation techniques and required materials.
• Analysis of current and potential applications in tissue regeneration.

Main Results:

• Overview of diverse sustained-release drug microsphere formulations and their properties.
• Detailed summary of various preparation methods and constituent materials.
• Compilation of key applications within tissue engineering, including regenerative medicine strategies.
• Identification of current limitations and future research directions.

Conclusions:

• Sustained-release drug microspheres represent a promising platform for targeted and prolonged drug delivery in tissue engineering.
• Further research into novel materials and fabrication techniques will enhance their efficacy and expand their clinical utility.
• This review provides valuable insights for researchers and practitioners in the field of drug delivery and regenerative medicine.