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Published on: February 16, 2018
Electrochemical selective annulative amino-ketalization and amino-oxygenation of 1,6-enynes
Xiao-Shuang Ji1, Hang-Dong Zuo1,2, Yi-Ting Shen1
1School of Chemistry & Materials Science, Jiangsu Normal University, Xuzhou, 221116, P. R. China. wjhao@jsnu.edu.cn.
Abstract:
A new electrochemical selective annulative amino-ketalization and amino-oxygenation of 1,6-enynes with disulfonimides and alcohols is reported, producing a series of functionalized benzofurans under catalyst- and oxidant-free conditions. The annulative aminoketalization proceeds with simple short-chain alcohols such as methanol, ethanol and n-propanol as O-nucleophilic reagents, while the reaction occurs in the annulative aminooxygenation direction in the presence of water and large steric sec-butyl alcohol (SBA).
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