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Updated: Aug 30, 2025

Making MR Imaging Child's Play - Pediatric Neuroimaging Protocol, Guidelines and Procedure
Published on: July 30, 2009
Imaging of Suspected Stroke in Children, From the AJR Special Series on Emergency Radiology
Luis O Tierradentro-García1, Alireza Zandifar1, Natalie L Ullman2
1Department of Radiology, Division of Neuroradiology, Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA 19104.
Insights
Pediatric stroke diagnosis is challenging due to overlapping symptoms. Neuroimaging is crucial for accurate diagnosis and differentiating stroke mimics in children.
Area of Science:
- Neurology
- Pediatric Medicine
- Medical Imaging
Background:
- Pediatric stroke, though uncommon, leads to significant short- and long-term adverse outcomes.
- Diagnostic delays in pediatric stroke are common due to overlapping symptoms with conditions like migraines and seizures.
- Accurate diagnosis relies on integrating clinical evaluation with advanced neuroimaging techniques.
Purpose of the Study:
- To review current neuroimaging protocols for diagnosing pediatric stroke in emergency settings.
- To compare the advantages and disadvantages of various neuroimaging modalities.
- To discuss predisposing conditions, stroke mimics, and age-specific diagnostic approaches.
Main Methods:
- Comprehensive review of neuroimaging workup for pediatric stroke.
- Analysis of different imaging modalities (e.g., MRI, CT) and their applications.
- Discussion of differential diagnoses, including stroke mimics.
Main Results:
- Neuroimaging is essential for confirming pediatric stroke and distinguishing it from mimics.
- Specific imaging techniques offer unique benefits and limitations in the pediatric population.
- Understanding predisposing factors and mimics aids in timely and accurate diagnosis.
Conclusions:
- Effective diagnosis of pediatric stroke requires a tailored neuroimaging strategy.
- Differentiating stroke from mimics is critical for appropriate management and improved outcomes.
- The approach to pediatric stroke diagnosis differs from that in adults.
Abstract:
Pediatric stroke encompasses different causes, clinical presentations, and associated conditions across ages. Although it is relatively uncommon, pediatric stroke presents with poor short- and long-term outcomes in many cases. Because of a wide range of overlapping presenting symptoms between pediatric stroke and other more common conditions, such as migraine and seizures, stroke diagnosis can be challenging or delayed in children. When combined with a comprehensive medical history and physical examination, neuroimaging plays a crucial role in diagnosing stroke and differentiating stroke mimics. This review highlights the current neuroimaging workup for diagnosing pediatric stroke in the emergency department, describes advantages and disadvantages of different imaging modalities, highlights disorders that predispose children to infarct or hemorrhage, and presents an overview of stroke mimics. Key differences in the initial approach to suspected stroke between children and adults are also discussed.
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