Echocardiography Parameters in Behcet's Disease, A Comparative Study.
Reza Salehi Manzari1, Zahra Mirfeizi2, Hoorak Poorzand3
1Mashhad University of Medical Sciences, Mashhad, Iran.
Current Rheumatology Reviews
|August 31, 2022
Summary
Echocardiography detected higher tricuspid regurgitation and elevated pulmonary artery pressure in Behçet
Area of Science:
- Cardiology
- Rheumatology
- Internal Medicine
Background:
- Behçet's disease (BD) is a chronic inflammatory condition with potential multi-organ effects.
- Cardiac involvement in BD, though uncommon, significantly impacts patient morbidity, mortality, and quality of life.
Purpose of the Study:
- To investigate echocardiographic abnormalities in patients with Behçet's disease who exhibit no cardiac symptoms.
- To assess cardiac function using echocardiography in asymptomatic BD patients.
Main Methods:
- A cross-sectional descriptive-analytic study conducted from 2015-2018.
- Inclusion of patients diagnosed with BD based on ISG criteria and a control group.
- Transthoracic echocardiography performed on all participants, with comparative analysis of echocardiographic parameters.
Main Results:
- Increased severity of aortic, mitral, and tricuspid regurgitation observed in the BD group compared to controls.
- Tricuspid regurgitation severity showed a statistically significant difference (p < 0.001).
- Systolic Pulmonary Artery Pressure (sPAP) was significantly higher in BD patients (24.6 mmHg) versus controls (22.81 mmHg) (p = 0.019).
Conclusions:
- Echocardiography is a valuable tool for assessing cardiac function, even in asymptomatic individuals with Behçet's disease.
- Moderate mitral and aortic regurgitation were exclusively found in BD patients.
- Long-term follow-up and further research are recommended.
