Related Experiment Video
Updated: Aug 30, 2025
06:13
Endoscopic Septoplasty with Limited Two-line Resection: Minimally Invasive Surgery for Septal Deviation
Published on: June 20, 2018
16.9K
Nasal Reconstruction in Granulomatosis with Polyangiitis: A Two Decade Review
Andres Gantous1, Rodrigo Fortunato Fernández-Pellón Garcia1
1Division of Facial Plastic and Reconstructive Surgery, Department of Otolaryngology-Head & Neck Surgery, Temerty Faculty of Medicine, University of Toronto, Toronto, Canada.
Facial Plastic Surgery & Aesthetic Medicine
|August 31, 2022
Summary
Rhinoplasty using cartilage grafts can improve breathing and appearance in Granulomatosis with polyangiitis (GPA) patients with saddle nose deformity. Surgery timing and graft choice are key factors for successful outcomes.
Area of Science:
- Otolaryngology
- Plastic Surgery
- Immunology
Background:
- Granulomatosis with polyangiitis (GPA) causes progressive nasal tissue destruction, leading to saddle deformity and obstruction.
- Numerous reconstructive techniques exist, but large-scale outcome data are limited.
Purpose of the Study:
- To evaluate complications and outcomes of rhinoplasty in patients with GPA.
- To assess patient satisfaction with appearance and nasal function post-reconstruction.
Main Methods:
- Retrospective review of 42 patients with GPA undergoing nasal reconstruction for saddle nose deformity (2005-2019).
- Primary use of costal cartilage and soft tissue grafts.
- Minimum 12-month follow-up for all included patients.
Main Results:
- 36 patients met inclusion criteria; all followed for ≥12 months.
- 6 patients (16.7%) required revision surgery (infection, GPA flare-ups).
- 5 patients experienced complications; overall satisfaction with appearance and breathing was assessed via questionnaire.
Conclusions:
- Strong cartilage grafts and appropriate surgical timing improve breathing and appearance in GPA patients.
- Rhinoplasty is a viable option for correcting saddle nose deformity in GPA.
- Further research on optimal surgical timing and graft materials is warranted.
