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Aortitis presenting as acute myeloid leukemia - A case report.

Branden Ireifej1, Majd Freijat2, David Song1

  • 1Icahn School of Medicine at Mount Sinai - Elmhurst Hospital Center, New York, USA.

Annals of Medicine and Surgery (2012)
|September 1, 2022
PubMed
Summary

Aortitis, inflammation of the aorta, can signal serious underlying conditions. This case highlights acute myeloid leukemia (AML) presenting initially as aortitis, emphasizing the need for broader differential diagnoses.

Keywords:
Acute myeloid leukemiaAortitisLarge cell vasculitis

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Area of Science:

  • Cardiovascular Medicine
  • Oncology
  • Rheumatology

Background:

  • Aortitis is often associated with large cell vasculitis.
  • It can be an initial presentation for various systemic diseases.

Observation:

  • A 53-year-old female presented with abdominal pain, nausea, fever, and headaches.
  • CT scan revealed an inflamed aorta, initially suspected as large cell vasculitis.

Findings:

  • The patient's aortitis was ultimately attributed to underlying acute myeloid leukemia (AML).
  • This case demonstrates a rare presentation of AML.

Implications:

  • Highlights the importance of considering malignancy, specifically hematologic cancers, in the differential diagnosis of aortitis.
  • Emphasizes the need for rheumatologists to consider non-vasculitic causes of aortitis.