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Updated: Jun 17, 2026

Murine Cervical Heart Transplantation Model Using a Modified Cuff Technique
Published on: October 12, 2014
Cardiac mass many years after heart transplantation-a case report
Lucia Dallapellegrina1,2, Edoardo Sciatti3, Enrico Vizzardi1,2
1Cardiology Unit, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy.
Insights
A rare case of late thrombus formation occurred in the neo-atrium after bi-atrial heart transplantation. This finding is unusual given the absence of atrial arrhythmia and prothrombotic medication use.
Area of Science:
- Cardiology
- Transplantation Surgery
Background:
- The bi-atrial surgical technique for heart transplantation can lead to postoperative complications.
- These include atrial dysfunction, sinus node issues, valvular problems, and atrial enlargement, increasing arrhythmia and thrombus risk.
Observation:
- This report details an unusual case of very late thrombus formation.
- The thrombus developed in the neo-atrium of a heart transplant recipient who underwent the bi-atrial technique.
Findings:
- The patient had no history of atrial arrhythmia.
- The patient had not taken any prothrombotic medications, making the thrombus formation noteworthy.
Implications:
- This case highlights the potential for late complications even in the absence of typical risk factors.
- Further research may be needed to understand the mechanisms of late thrombus formation in bi-atrial heart transplant recipients.
Abstract:
The bi-atrial surgical technique of heart transplantation is associated with postoperative atrial dysfunction, sinus node dysfunction, valvular dysfunction, and bi-atrial enlargement predisposing to atrial arrhythmia with thrombus formation. This report deals with a very late thrombus formation in the neo-atrium of a heart transplanted using the bi-atrial technique. The absence of arrhythmia and absence of any history of intake of prothrombotic medications make it noteworthy.
Supplementary Information:
The online version contains supplementary material available at 10.1007/s12055-022-01362-x.
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