Modeling the Transmission Dynamics of COVID-19 Among Five High Burden African Countries

Sebwedin Surur Jemal1, Bizuwork Derebew Alemu1

  • 1Department of Statistics, College of Natural and Computational Sciences, Mizan-Tepi University, Tepi, Ethiopia.

Clinical Epidemiology
|September 2, 2022
PubMed

Insights

Vaccination can significantly reduce coronavirus disease-19 (COVID-19) transmission in five high-burden African nations. Vaccinating half the population could prevent millions of infections and deaths over the next 30 years.

Area of Science:

  • Epidemiology
  • Mathematical Modeling
  • Public Health

Background:

  • COVID-19 has caused significant mortality and morbidity globally, impacting 58 African countries.
  • Five African nations (South Africa, Morocco, Tunisia, Ethiopia, Libya) face high burdens of COVID-19 cases and fatalities.
  • Understanding COVID-19 transmission dynamics in these high-burden countries is crucial.

Purpose of the Study:

  • To analyze the transmission dynamics of COVID-19 and its variants in five high-burden African countries.
  • To project the future impact of COVID-19 in these regions.
  • To evaluate the effectiveness of vaccination as a control strategy.

Main Methods:

  • A deterministic, year-structured susceptible, infected, mild severe, critical severe, and recover (SIMCR) compartmental model was employed.
  • The model partitions the population based on epidemiological states.
  • The study simulated COVID-19 transmission dynamics over a 30-year period.

Main Results:

  • The model predicted approximately 86 million COVID-19 infections and millions of deaths in the five countries over 30 years.
  • Vaccination of half the population is projected to decrease infected individuals by millions.
  • Specifically, vaccination could prevent 17,212,405 infections in South Africa, Morocco, Tunisia, Ethiopia, and Libya.

Conclusions:

  • The SIMCR model effectively describes COVID-19 transmission in the studied African countries.
  • Vaccination is identified as the most effective strategy to control and reduce COVID-19 transmission.
  • Widespread vaccination can avert millions of infections and deaths, significantly mitigating the pandemic's impact in Africa.
Abstract

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