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Related Concept Videos

Microtubule Associated Motor Proteins01:32

Microtubule Associated Motor Proteins

Eukaryotic cells have different motor proteins for transporting various cargo within the cell. These motor proteins differ based on the filament they associate with, the direction they move within the cell, and the type of cargo they transport. Motor proteins that associate with microtubules are known as microtubule-associated motor proteins. There are two families of microtubule-associated motor proteins —Kinesins and Dyneins. Both these proteins assist in the transport of cellular cargos...

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Multi-Level Asymmetric Mesoporous Nanochannels for Photothermal-Regulated Dopamine Sensing.

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Updated: Jun 17, 2026

Folding and Characterization of a Bio-responsive Robot from DNA Origami
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A Biomolecular Toolbox for Precision Nanomotors.

Joel Yong1, Albert S Mellick2,3, John Whitelock2

  • 1School of Chemical Engineering and Australian Centre for NanoMedicine, The University of New South Wales, Kensington, New South Wales, 2052, Australia.

Advanced Materials (Deerfield Beach, Fla.)
|September 2, 2022
PubMed
Summary

Nanomotors combined with nanomedicine offer new solutions for cancer diagnosis and therapy. This review provides a toolbox and biological context for future nanomotor research in oncology.

Keywords:
cancercell adhesion moleculesnanomedicinenanomotorstargeting

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Area of Science:

  • Biomedical Engineering
  • Nanotechnology
  • Oncology

Background:

  • Passive nanoparticles face challenges in cancer diagnosis and therapy.
  • Nanomotors offer a novel approach to overcome limitations in nanomedicine.
  • Understanding cancer cell biology is crucial for effective nanomotor application.

Purpose of the Study:

  • To introduce nanomotor and nanomedicine researchers to cancer cell biology and biochemistry.
  • To provide a comprehensive overview of nanomotor applications in cancer diagnosis and therapy.
  • To offer a biomolecular targeting toolbox for selecting appropriate targeting molecules and cell surface targets.

Main Methods:

  • Review of current nanomotor technology for cancer applications.
  • Collated biomolecular targeting toolbox with various targeting molecules and cell surface targets.
  • Analysis of cell membrane compositions and extracellular surfaces.

Main Results:

  • Current state-of-the-art of nanomotors in cancer therapy and diagnosis.
  • Overview of available targeting molecules for high-affinity and specific targeting.
  • Glimpse into current clinical therapies and technologies.

Conclusions:

  • Nanomotors hold significant promise for advancing cancer diagnosis and therapy.
  • A deeper understanding of cancer biology is essential for optimizing nanomotor design and function.
  • Future research should focus on integrating nanomotor technology with precision nanomedicine for improved clinical outcomes.