Preoperative factors analysis on root development after regenerative endodontic procedures: a retrospective study

Area of Science:

• Endodontics
• Paediatric Dentistry
• Regenerative Medicine

Background:

• Regenerative endodontic procedures (REPs) are clinically successful for immature permanent teeth with pulp necrosis.
• REPs promote root development, but preoperative factors influencing this outcome require further investigation.

Purpose of the Study:

• To investigate preoperative factors influencing root development following regenerative endodontic procedures (REPs).

Main Methods:

• Retrospective analysis of 116 teeth in 110 patients treated with REPs.
• Collected data on aetiology, age, diagnosis, and initial root morphology.
• Statistical analysis using Fisher's exact test and multivariate logistic regression.

Main Results:

• Overall root development rate was 89.7%.
• Dens evaginatus (98.8%) showed higher root development than trauma (67.6%) (P < 0.01).
• Larger apical foramen size (>3 mm) in trauma cases correlated with better root development (P < 0.01). Aetiology was significantly correlated with REPs outcomes (OR: 0.07, P < 0.05).

Conclusions:

• Aetiology is a significant factor influencing root development in regenerative endodontic procedures.
• REPs demonstrate superior root development in dens evaginatus cases compared to trauma cases.