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Aggressive angiomyxoma: The first case report in skull
Zexin Cao1,2, Lifeng Miao3, Min Liu4
1Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.
Frontiers in Surgery
|September 5, 2022
Summary
Aggressive angiomyxoma, a rare tumor, typically affects adult women. This study details a rare pediatric case of aggressive angiomyxoma in a 2-year-old girl
Area of Science:
- Oncology
- Pathology
Background:
- Aggressive angiomyxoma (AAM) is a rare mesenchymal tumor predominantly affecting the pelvic and perineal soft tissues of women of reproductive age.
- While benign, AAM can exhibit localized invasion, making complete surgical resection challenging due to its invasive nature and poorly defined capsule.
Observation:
- This report presents a rare case of aggressive angiomyxoma in a 2-year-old girl.
- The tumor presented as a cranial mass, leading to craniocerebral compression and symptoms like headaches.
- Surgical intervention was performed, but the tumor recurred one year post-operatively.
Findings:
- This case highlights the unusual presentation of aggressive angiomyxoma in a pediatric patient.
- The cranial location and craniocerebral compression underscore the potential for AAM to occur in extragenital sites.
- Recurrence after surgery indicates the infiltrative nature of the tumor, even in this rare pediatric presentation.
Implications:
- This case expands the known clinical spectrum of aggressive angiomyxoma to include pediatric cranial presentations.
- It emphasizes the importance of considering AAM in the differential diagnosis of pediatric cranial masses.
- The findings suggest that vigilance for recurrence is crucial following surgical management of AAM, regardless of patient age or tumor location.
