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Systematic MRI in persistent post-Covid-19 olfactory dysfunction should be reassessed.

Ioana Brudasca1, Quentin Lisan2, Romain Tournegros1

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Magnetic resonance imaging (MRI) may not be necessary for persistent olfactory dysfunction (OD) following COVID-19. A study found MRI did not change diagnosis or treatment for patients with post-SARS-CoV-2 OD.

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Area of Science:

  • Neurology
  • Radiology
  • Infectious Diseases

Background:

  • Persistent olfactory dysfunction (OD) is a common sequela of SARS-CoV-2 infection.
  • Magnetic resonance imaging (MRI) is typically recommended for persistent OD to determine the cause.
  • The role of MRI in COVID-19-related OD requires evaluation due to the high prevalence of this symptom post-infection.

Discussion:

  • This study investigated the impact of systematic MRI on managing patients with persistent OD after COVID-19.
  • Researchers assessed if MRI findings correlated with the severity of olfactory dysfunction (OD) and olfactory bulb (OB) volume.
  • The study included 67 adult patients experiencing OD for over two months after SARS-CoV-2 infection.

Key Insights:

  • In 82% of cases, MRI scans of patients with persistent post-COVID-19 OD were interpreted as normal.
  • No significant differences in visual MRI analysis or olfactory bulb volume were found across different severities of hyposmia.
  • Crucially, undergoing MRI did not lead to any changes in the diagnosis or treatment plan for any patient.

Outlook:

  • Systematic MRI may be an unnecessary diagnostic step for patients with persistent olfactory dysfunction that emerged shortly after a confirmed SARS-CoV-2 infection.
  • Further research could explore alternative, potentially more cost-effective diagnostic strategies for post-viral olfactory dysfunction.
  • This finding has significant public health implications, potentially streamlining the management of a widespread post-COVID-19 symptom.