Method for generating transparent porcine tibia showing the intraosseous artery

Area of Science:

• Biomedical Engineering
• Anatomical Science
• Surgical Research

Background:

• Nonunion after tibial fracture surgery is linked to poor blood supply.
• Current methods lack clear visualization of the intraosseous artery.
• This hinders surgical protection, reconstruction, and research.

Purpose of the Study:

• To develop a transparent specimen for clear display of the tibia's intraosseous artery.
• To improve visualization for surgical and research applications.

Main Methods:

• Utilized pig tibias, epoxy resin perfusion, and acid-alkali etching.
• Employed 3D scanning and printing for transparent specimen creation.
• Detailed observation of intraosseous artery distribution and branching patterns.

Main Results:

• Successfully created a transparent porcine tibia specimen with visible intraosseous arteries.
• The nutrient artery's entry point and branching pattern within the tibia were accurately mapped.
• 3D printing preserved the tibia's external shape and internal vascular structures.

Conclusions:

• The developed perfusion-corrosion method provides a clear anatomical reference for intraosseous arteries.
• Offers a theoretical basis for new internal fixation and lower tibia blood supply reconstruction techniques.
• Enhances understanding for surgeons and researchers in tibial fracture management.