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Updated: Aug 29, 2025

A Data-Driven Approach to Quantifying Immune States in Sepsis
Published on: February 7, 2025
Quality Improvement to Promote Sepsis Reassessment: The Sepsis Reassessment Protocol Improvement Project (SRPIP)
Jana P DeGregoris1, Lyza Bandong, Tameka White
1Center for Advanced Medicine & Surgery, White Plains Hospital, Montefiore Health System, White Plains, New York (Dr DeGregoris); The Mount Sinai Hospital, New York City, New York (Dr Bandong); COVID Isolation and Quarantine Sites Housing Works INC, New York City, New York (Dr White); and New York University Rory Meyers College of Nursing, New York City (Dr Brennan).
Background:
Implementation of the Surviving Sepsis Campaign (SSC) guidelines into practice has demonstrated improved outcomes.
Local Problem:
Compliance with a sepsis protocol, based on the SSC guidelines, in an urban teaching hospital was below the national average.
Methods:
A pre- and posttest intervention design was used to improve clinician knowledge, confidence, and compliance with the protocol.
Interventions:
Educational modules were developed on the SSC guidelines and reminder system alerts (RSA) for timely revaluation of patients with sepsis and lactate monitoring were implemented.
Results:
A total of 33 (48%) clinicians participated. There was an increase in knowledge, documentation of sepsis reassessment, and serum lactate monitoring. There was an improvement in clinician perceptions following the initiative.
Conclusions:
The results demonstrate that education, combined with RSAs, can improve protocol knowledge and compliance.
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