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A Patient-Derived Xenograft Model for Venous Malformation
Published on: June 15, 2020
How we approach localized vascular anomalies
Kristy S Pahl1, Waleska M Pabon-Ramos2, Michael R Jeng3
1Department of Pediatrics, Duke University Medical Center, Durham, North Carolina, USA.
Abstract:
Vascular anomalies are a group of disorders divided into two distinct subtypes: vascular tumors and vascular malformations. Vascular tumors are proliferative in nature, while malformations are nonproliferative. Simple, localized vascular malformations refer to a group of malformations that are localized to a single area of involvement. These simple malformations include capillary, lymphatic, venous, and arteriovenous malformations. The pediatric hematologists and oncologists are becoming increasingly involved in the diagnosis and management of these disorders. This review presents four cases as a means to discuss the diagnosis, clinical and imaging features, and management strategies of simple, localized vascular malformations.
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