Related Experiment Video For chronotherapy
Updated: Aug 29, 2025

In Vitro Bioluminescence Assay to Characterize Circadian Rhythm in Mammary Epithelial Cells
Published on: September 28, 2017
Circadian rhythm in prostate cancer: time to take notice of the clock
Wei-Zhen Zhu1, Qi-Ying He1, De-Chao Feng1
1Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu 610041, China.
Abstract:
The circadian clock is an evolutionary molecular product that is associated with better adaptation to changes in the external environment. Disruption of the circadian rhythm plays a critical role in tumorigenesis of many kinds of cancers, including prostate cancer (PCa). Integrating circadian rhythm into PCa research not only brings a closer understanding of the mechanisms of PCa but also provides new and effective options for the precise treatment of patients with PCa. This review begins with patterns of the circadian clock, highlights the role of the disruption of circadian rhythms in PCa at the epidemiological and molecular levels, and discusses possible new approaches to PCa therapy that target the circadian clock.
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