Related Experiment Video
Updated: Jul 1, 2026
03:55
Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
Published on: June 9, 2023
599
Case report: Large follicular thyroid carcinoma with multiple cervical lymph node metastases
Fei Ye1, Liyan Liao2, Wanlin Tan3,4
1Department of Thyroid Surgery, The Second Xiangya Hospital, Central South University, Changsha, China.
Frontiers in Surgery
|September 9, 2022
Summary
This case report highlights a rare instance of large follicular thyroid carcinoma (FTC) with extensive lymph node metastasis but no distant spread. Advanced imaging and pathology confirmed the diagnosis in a 66-year-old male patient.
Area of Science:
- Oncology
- Endocrinology
- Pathology
Background:
- Follicular thyroid carcinoma (FTC) typically metastasizes hematogenously.
- Regional lymph node metastasis is uncommon in FTC, especially in large tumors without distant spread.
Observation:
- A 66-year-old male presented with a 20-year history of a progressively enlarging thyroid mass causing tracheal compression.
- Imaging modalities including ultrasonography, CT, MR, and PET/CT were utilized to assess the thyroid and surrounding structures.
- The patient underwent total thyroidectomy with comprehensive lymph node dissection.
Findings:
- Histopathological and immunohistochemical evaluations confirmed FTC.
- The tumor exhibited extensive cervical lymph node metastases, predominantly in lateral compartments.
- No distant metastases were identified.
Implications:
- This case underscores the importance of considering diverse metastatic patterns in follicular thyroid carcinoma.
- Comprehensive imaging and pathological assessment are crucial for accurate staging and treatment planning.
- Such rare presentations challenge conventional understanding of FTC metastatic behavior.
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