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Spectrum scores: Toward a better definition of de-escalation
Daniel T Ilges1, David J Ritchie2, Tamara Krekel2
1Mayo Clinic Hospital, Phoenix, Arizona.
Abstract:
Spectrum scores measure antimicrobial utilization while also quantifying the spectrum of activity. Accordingly, changes in spectrum score can be used to identify antimicrobial de-escalation. We show that spectrum-score-based de-escalation has a 95.7% positive percentage agreement and 81.6% negative percentage agreement versus de-escalation defined as stopping either antistaphylococcal or antipseudomonal agents.
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