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    Bitbox offers a secure, web-based solution for exchanging large biomedical imaging datasets. This system addresses technical and regulatory challenges in medical data transfer, facilitating multi-site research.

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    Area of Science:

    • Digital Health and Medical Informatics
    • Biomedical Imaging and Data Transfer

    Background:

    • Modern healthcare digitization necessitates robust medical data exchange.
    • Biomedical imaging data volumes are rapidly increasing due to multi-site collaborations.
    • Existing systems face technical and regulatory hurdles in secure data transfer.

    Purpose of the Study:

    • To present Bitbox, a novel web-based application for secure medical imaging data exchange.
    • To demonstrate a reliable and straightforward service for transferring diverse biomedical data.
    • To showcase Bitbox's utility in a large-scale clinical research project.

    Main Methods:

    • Development of a web-based application, Bitbox, for secure data transfer.
    • Implementation of a system capable of handling large volumes and diverse types of imaging and non-imaging data.
    • Utilizing Bitbox for data aggregation from independent external sites to a centralized server.

    Main Results:

    • Bitbox provides a reliable and straightforward service for secure exchange of medical imaging data.
    • The system successfully transfers both imaging and non-imaging data from various sources.
    • Demonstrated application in the COVID-19 Clinical Neuroscience Study (COVID-CNS) project.

    Conclusions:

    • Bitbox effectively overcomes technical and regulatory bottlenecks in biomedical data exchange.
    • The application facilitates secure and efficient transfer of complex medical data for research.
    • Bitbox is a valuable tool for multi-site studies, exemplified by its use in COVID-CNS.