Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Gastrointestinal Motility Disorders01:20

Gastrointestinal Motility Disorders

566
Gastrointestinal or GI motility disorders are characterized by irregular gastrointestinal tract movements, disrupting food transit from the mouth to the anus. They are caused by damage or dysfunction in gut muscles or nerves. These disorders can cause symptoms such as severe constipation, diarrhea, abdominal pain, and swallowing difficulties. Disorders can affect any segment of the GI tract and range widely in severity, from common conditions like GERD to life-threatening conditions like...
566
Drugs Affecting GI Tract Motility: Dopamine Receptor Antagonists01:28

Drugs Affecting GI Tract Motility: Dopamine Receptor Antagonists

553
Prokinetic agents are specialized medications that stimulate gastrointestinal (GI) motility, promoting food movement through the GI tract. Dopamine, an inhibitory neurotransmitter, plays a significant role in this process, reducing GI motility and indirectly controlling the speed of digestion. Dopamine receptor antagonists, such as metoclopramide and domperidone, offer a unique advantage as prokinetic agents. By blocking the dopamine receptors, these drugs increase GI motility, improving food...
553
Gastric Motility01:16

Gastric Motility

1.1K
Gastric motility is the coordinated contraction and relaxation of stomach muscles that convert ingested food into chyme, a semi-liquid substance ready for further digestion in the intestines. The process begins with the vagus nerve inducing the relaxation of the smooth muscles in the fundus and body of the stomach, allowing these regions to expand and accommodate up to approximately 1.5 liters of food and liquid.
Peristaltic Waves and Chyme Formation
Upon food entry, the stomach initiates...
1.1K
Drugs Affecting GI Tract Motility: Serotonin Receptor Agonists01:23

Drugs Affecting GI Tract Motility: Serotonin Receptor Agonists

378
Serotonin, a crucial neurotransmitter synthesized by enterochromaffin cells, plays a cardinal role in regulating gastrointestinal (GI) motility. With over 90% of the body's total serotonin in the GI tract, its influence on digestive processes is profound. Serotonin is swiftly released upon various stimuli, such as food boluses or certain drugs, triggering intrinsic sensory neurons in the myenteric plexus and extrinsic vagal and spinal sensory neurons. This leads to the activation of the...
378
Gastric Emptying01:16

Gastric Emptying

1.3K
Gastric emptying occurs when the stomach gradually releases chyme into the duodenum. When the stomach is distended, it triggers the release of gastrin, a hormone that promotes gastric acid secretion to aid in digestion. Additionally, stomach distension contributes to peristaltic waves that propel gastric contents toward the pyloric region. The gastroenteric reflex, on the other hand, primarily stimulates peristalsis in the intestines, facilitating the movement of contents further along the...
1.3K
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding01:15

Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding

261
Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
261

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Stage-Dependent Prognostic Impact of Younger Age in Gastric Cancer: A Nationwide Cohort Study.

Journal of gastric cancer·2026
Same author

Expert Clinical Consensus on Body Surface Gastric Mapping Phenotypes for Gastroduodenal Disorders: 'Auckland Classification' v1.0.

Neurogastroenterology and motility·2026
Same author

RE: Do Cannabis Users Require More Anesthesia During Third Molar Removal Under Intravenous General Anesthesia When Compared to Nonusers?

Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons·2026
Same author

Transcriptomics profiles in intestinal sulfide overproduction, small intestinal bacterial overgrowth, and intestinal methanogen overgrowth.

mSystems·2026
Same author

Risk of acute kidney injury in hospitalized patients with inflammatory bowel disease: a systematic review and meta-analysis.

Journal of the Canadian Association of Gastroenterology·2026
Same author

Long-Term Outcomes of Mucosal Early Gastric Cancer with Lymphatic Invasion as the Sole Non-Curative Factor After Endoscopic Submucosal Dissection.

Cancers·2026

Related Experiment Video

Updated: Aug 29, 2025

Author Spotlight: Alleviating Nausea and Vomiting in Pregnancy with Safe and Effective Auricular Acupuncture
05:33

Author Spotlight: Alleviating Nausea and Vomiting in Pregnancy with Safe and Effective Auricular Acupuncture

Published on: August 4, 2023

1.6K

Gastroparesis in pregnancy.

Sarvee Moosavi1, Yang Won Min2, Melissa Wong3

  • 1Division of Gastroenterology, Department of Medicine, Vancouver General Hospital, The University of British Columbia, Vancouver, Canada.

American Journal of Obstetrics and Gynecology
|September 11, 2022
PubMed
Summary
This summary is machine-generated.

Pregnancy complicates gastroparesis management due to limited data and trial exclusions. This review addresses knowledge gaps and safe therapeutic options for pregnant women with gastroparesis.

Keywords:
gastroparesispregnancy

More Related Videos

Fabrication and Implantation of Miniature Dual-element Strain Gages for Measuring In Vivo Gastrointestinal Contractions in Rodents.
09:29

Fabrication and Implantation of Miniature Dual-element Strain Gages for Measuring In Vivo Gastrointestinal Contractions in Rodents.

Published on: September 18, 2014

10.4K
Assessment of Gastric Emptying in Non-obese Diabetic Mice Using a [13C]-octanoic Acid Breath Test
12:24

Assessment of Gastric Emptying in Non-obese Diabetic Mice Using a [13C]-octanoic Acid Breath Test

Published on: March 23, 2013

13.8K

Related Experiment Videos

Last Updated: Aug 29, 2025

Author Spotlight: Alleviating Nausea and Vomiting in Pregnancy with Safe and Effective Auricular Acupuncture
05:33

Author Spotlight: Alleviating Nausea and Vomiting in Pregnancy with Safe and Effective Auricular Acupuncture

Published on: August 4, 2023

1.6K
Fabrication and Implantation of Miniature Dual-element Strain Gages for Measuring In Vivo Gastrointestinal Contractions in Rodents.
09:29

Fabrication and Implantation of Miniature Dual-element Strain Gages for Measuring In Vivo Gastrointestinal Contractions in Rodents.

Published on: September 18, 2014

10.4K
Assessment of Gastric Emptying in Non-obese Diabetic Mice Using a [13C]-octanoic Acid Breath Test
12:24

Assessment of Gastric Emptying in Non-obese Diabetic Mice Using a [13C]-octanoic Acid Breath Test

Published on: March 23, 2013

13.8K

Area of Science:

  • Gastroenterology
  • Obstetrics
  • Pharmacology

Background:

  • Gastroparesis is a prevalent functional gastrointestinal disorder disproportionately affecting women of childbearing age.
  • Limited data and specific guidelines exist regarding gastroparesis epidemiology, disease progression, and maternal-fetal outcomes during pregnancy.
  • Pregnant and breastfeeding women are often excluded from clinical trials, complicating treatment decisions.

Approach:

  • This systematic review synthesizes current literature on the bidirectional impact of pregnancy and gastroparesis.
  • It evaluates the efficacy and safety of pharmacologic and non-pharmacologic therapies for gastroparesis.
  • Emphasis is placed on evidence-based dietary management strategies suitable for pregnant patients.

Key Points:

  • Pregnancy can alter gastroparesis symptoms and vice versa, requiring careful monitoring.
  • Metoclopramide is the only therapy with some indication, but safety in pregnancy is a concern.
  • Dietary modifications are crucial, focusing on easily digestible and nutrient-dense foods.

Conclusions:

  • There is a significant need for more research on gastroparesis in pregnancy.
  • Healthcare providers must carefully weigh risks and benefits of available treatments.
  • Individualized management plans incorporating safe dietary approaches are essential for pregnant women with gastroparesis.