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Related Experiment Video

Updated: Aug 29, 2025

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
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Update on imaging modalities for ocular surface pathologies.

Osmel P Alvarez1, Anat Galor2, Ghada AlBayyat1

  • 1Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami, Miami, FL, USA.

Current Ophthalmology Reports
|September 12, 2022
PubMed
Summary
This summary is machine-generated.

Recent advancements in ocular imaging, including micro-ocular coherence tomography and ocular coherence tomography angiography, enhance the detection of ocular surface pathologies. These technologies, alongside AI, offer improved visualization and diagnosis.

Keywords:
Ocular surface imaginganterior segment optical coherence tomographyanterior segment optical coherence tomography angiographyconfocal microscopyocular surface pathologiesultrasound biomicroscopy

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Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Biomedical Engineering

Background:

  • Ocular surface pathologies require accurate and early detection.
  • Advanced imaging techniques are crucial for diagnosing and monitoring these conditions.

Purpose of the Study:

  • To review recent studies on imaging modalities for ocular surface pathologies.
  • To highlight the utility of novel and established imaging technologies.

Main Methods:

  • Review of recent scientific literature on ocular surface imaging.
  • Focus on technologies such as micro-Ocular Coherence Tomography (μOCT), Ocular Coherence Tomography Angiography (OCTA), and in vivo confocal microscopy (IVCM).
  • Exploration of Artificial Intelligence (AI) applications in conjunction with imaging.

Main Results:

  • μOCT provides high-resolution imaging of corneal structures.
  • OCTA aids in early detection of limbal stem cell deficiency.
  • IVCM evaluates corneal nerve metrics and morphology.
  • AI combined with imaging technologies enhances pathology detection and visualization.

Conclusions:

  • Anterior segment optical coherence tomography (AS-OCT), OCTA, ultrasound biomicroscopy, and IVCM are valuable for ocular surface imaging.
  • AI integration shows promise for reliable ocular surface pathology detection.
  • Continued development of μOCT technology is expected to improve its clinical utility.