NTRK3 mutation in secretory carcinoma of the parotid gland: A Case report
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Updated: Aug 29, 2025

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
Fahad AlKaabba1, Abdurahman Alloghbi2,3, Yazeed Deajim2
1Department of Medicine University of Maryland Medical Center Baltimore MD USA.
Abstract:
Mammary analog secretory carcinoma (MASC) is a newly described carcinoma with a molecular hallmark of ETV6-NTRK3 fusion that promotes oncogenesis. While MASC histopathology was well-studied in the literature, clinical behavior remains unstudied. We present a 22-year-old man with painless parotid mass, which was diagnosed as salivary gland cancer, MASC subtype.
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