Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Experimental genital trichomoniasis in the squirrel monkey (Saimiri sciureus).

W A Gardner, D E Culberson, J M Scimeca

    Genitourinary Medicine
    |June 1, 1987
    PubMed
    Summary

    Squirrel monkeys can model human vaginal trichomoniasis. Researchers found that intestinal trichomonads in these primates are easily removed, clearing confusion and validating their use in studying this infection.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Heredity in Nervous Diseases and Its Social Bearings.

    Atlanta journal-record of medicine·2022
    Same author

    Detection and cultivation of intestinal trichomonads of squirrel monkeys (Saimiri sciureus).

    American journal of primatology·2020
    Same author

    Determination of lactogenic activity in the serum of the squirrel monkey (Saimiri boliviensis) using the Nb2 lymphoma bioassay.

    American journal of primatology·2020
    Same author

    Confirmation of ovulation and characterization of luteinizing hormone and progesterone secretory patterns in cycling, isosexually housed Bolivian squirrel monkeys (Saimiri boliviensis boliviensis).

    American journal of primatology·2020
    Same author

    Characterization of prolactin and growth hormone immuno- and bioactivities in the pituitary gland and serum of the squirrel monkey (Saimiri boliviensis boliviensis).

    American journal of primatology·2020
    Same author

    Cryopreservation and in vitro culture of white-tailed deer ovarian tissue.

    Theriogenology·2018

    Area of Science:

    • Primate models in infectious disease research
    • Parasitology and tropical diseases
    • Urogenital health and disease

    Background:

    • The squirrel monkey (Saimiri sciureus) has been considered for modeling human urogenital trichomoniasis.
    • Previous concerns about naturally occurring vaginal trichomonads in squirrel monkeys hindered their acceptance as a model.
    • Vaginal trichomoniasis is a common human infection with significant public health implications.

    Purpose of the Study:

    • To investigate and clarify the origin of trichomonads found in squirrel monkey vaginas.
    • To determine the suitability of squirrel monkeys as a reliable model for experimental vaginal trichomoniasis.
    • To assess the influence of hormonal status on the establishment of experimental trichomoniasis in primates.

    Main Methods:

    Related Experiment Videos

    • Experimental inoculation of squirrel monkeys with Trichomonas vaginalis.
    • Assessment of trichomonad presence and eradication in vaginal and intestinal tracts.
    • Correlation of experimental infection success with the hormonal status of the primates.

    Main Results:

    • Naturally occurring vaginal trichomonads in squirrel monkeys were identified as easily eradicable organisms of intestinal origin.
    • This finding resolves previous confusion regarding the suitability of the squirrel monkey model.
    • Experimental trichomoniasis establishment was found to be dependent on the hormonal status of the primates.

    Conclusions:

    • The squirrel monkey is a viable and validated model for studying vaginal trichomoniasis.
    • The hormonal status of primates is a critical factor for successful experimental infection.
    • This model can aid in understanding the pathogenesis and developing treatments for vaginal trichomoniasis.