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Related Experiment Video

Updated: Aug 28, 2025

Roux-en-Y Gastric Bypass Operation in Rats
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Long-Term Outcomes after Adolescent Bariatric Surgery.

Nestor de la Cruz-Muñoz1, Luyu Xie2,3, Hallie J Quiroz1

  • 1From the Dewitt Daughtry Family Department of Surgery, University of Miami Miller School of Medicine, Miami, FL (de la Cruz-Muñoz, Quiroz, Kutlu).

Journal of the American College of Surgeons
|September 14, 2022
PubMed
Summary
This summary is machine-generated.

Metabolic and bariatric surgery (MBS) in adolescents shows sustained weight loss and significant comorbidity remission over a decade. These long-term outcomes support MBS as a safe and effective treatment for severe obesity in young people.

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Area of Science:

  • Adolescent Medicine
  • Bariatric Surgery Outcomes
  • Obesity Treatment

Background:

  • Metabolic and bariatric surgery (MBS) is recognized as a safe and effective treatment for severe adolescent obesity.
  • However, limited long-term data (over 10 years) exist to confirm sustained positive outcomes following adolescent MBS.

Purpose of the Study:

  • To evaluate the long-term efficacy and safety of metabolic and bariatric surgery (MBS) in adolescents.
  • To assess sustained weight reduction, comorbidity status, functional outcomes, and complications 10-18 years post-surgery.

Main Methods:

  • A telehealth follow-up study included 96 patients who underwent MBS at age 21 or younger between 2002-2010.
  • Evaluated outcomes included body weight, comorbidity remission, functional status, and long-term complications up to 18 years post-MBS.
  • Surgical procedures were primarily Roux-en-Y gastric bypass (RYGB) or laparoscopic adjustable gastric banding (LAGB).

Main Results:

  • Mean body weight reduction was 31.3% at a mean follow-up of 14.2 years post-MBS.
  • 100% remission rates were observed for pre-existing hyperlipidemia, asthma, and diabetes/hyperglycemia.
  • Significant reductions in hypertension, sleep apnea, gastroesophageal reflux disease, and depression were also documented.

Conclusions:

  • Metabolic and bariatric surgery in adolescents leads to significant, sustained weight reduction and comorbidity remission.
  • Low rates of long-term complications were observed, supporting MBS as a viable option for sustained health improvements into adulthood.
  • These findings underscore the importance of considering MBS for adolescents with severe obesity seeking long-term health benefits.