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A case of topical imiquimod induced fatigue
Justin Raman1, Elizabeth Bisbee2, Tricia A Missall1
1Department of Dermatology, University of Florida College of Medicine, Gainesville, FL, USA.
Abstract:
Topical imiquimod is used for a variety of common dermatologic lesions, including melanoma in-situ. As an immunomodulator, it is relatively well tolerated with minimal side effects, including scaling, erythema, and edema. Here we present a rare systemic adverse effect, where our patient experienced debilitating severe fatigue when applying imiquimod to a single lesion. Clinicians should be mindful of this side effect and counsel patients appropriately.
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