Related Experiment Video
Updated: Aug 18, 2026

Laparoscopic Pancreatoduodenectomy With Modified Blumgart Pancreaticojejunostomy
Published on: June 17, 2018
Incidentally Detected Extramedullary Plasmacytoma of the Gallbladder: A Case Report and Literature Review
Hideki Ono1, Shinichi Iwatsu1, Eiichi Otsuka2
1Department of Gastroenterology, Oita Prefectural Hospital, Japan.
Abstract:
Extramedullary plasmacytoma (EMP) can rarely occur in conjunction with multiple myeloma (MM). EMPs are usually detected in the upper aerodigestive tract (UAD) but can also occur along the digestive tract. However, the involvement of gallbladder is uncommon. Gastrointestinal tract symptoms often lead to the diagnosis of EMP in the gallbladder. An 81-year-old man was referred to our hospital with suspected primary gallbladder carcinoma. He was subsequently operated on, and the pathological findings showed EMP of the gallbladder without MM.
Insights
Extramedullary plasmacytoma, a rare plasma cell tumor, can occur in the gallbladder. This case highlights gallbladder extramedullary plasmacytoma without multiple myeloma, presenting with gastrointestinal symptoms.
Area of Science:
- Oncology
- Gastroenterology
- Pathology
Background:
- Extramedullary plasmacytoma (EMP) is a rare plasma cell neoplasm.
- While typically found in the upper aerodigestive tract, EMP can occur elsewhere in the digestive system.
- Gallbladder involvement by EMP is exceptionally uncommon.
Conclusions:
- Extramedullary plasmacytoma is a rare differential diagnosis for gallbladder masses.
- Gallbladder EMP can present with gastrointestinal symptoms mimicking malignancy.
- Surgical resection and pathological analysis are crucial for accurate diagnosis.
More Related Videos
Related Concept Videos
Gallbladder
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins the common...
Cholecystitis

