Related Experiment Video
Updated: Aug 28, 2025

Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
Published on: February 9, 2024
Progressive loss of the thyroid tissue integrity visualised by serial CT scans
Hiroyuki Koyama1, Rei Hattori1, Hiroyuki Sagawa2
1Gastroenterology and Metabolism, Graduate School of Medical Sciences and Medical School, Nagoya City University, Nagoya, Japan.
Nivolumab can cause thyroid dysfunction, including thyrotoxicosis and hypothyroidism, in patients with cancer. Thyroid CT density may serve as an early indicator of developing thyroiditis in patients receiving immune checkpoint inhibitors.
Area of Science:
- Oncology
- Endocrinology
- Radiology
Background:
- Immune checkpoint inhibitors (ICIs) like nivolumab are increasingly used in cancer treatment.
- Functional thyroid disease is a known side effect of ICI therapy.
- Early detection of thyroiditis is crucial for appropriate management.
Related Concept Videos
The Thyroid Gland
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
Computed Tomography
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Synthesis and Regulation of Thyroid Hormones
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
Imaging Studies for Cardiovascular System V: CT

